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Editorial Reviews

Four years after his smash comedy hit, The Paleface, Bob Hope (My Favorite Brunette) returned to the screen as Junior Potter, son of Painless Peter Potter, the hapless hero of the first film. The Harvard-bred Junior heads out west to claim his father's inheritance. Also returning for the sequel, but in a different role, is the beautiful Jane Russell (The Outlaw) as a gunfighter named Mike The Torch Delroy who continually has to save our hapless hero with help from the king of the singing cowboys, Roy Rogers (Sunset in the West) and legendary horse Trigger (Trigger, Jr.) who team up with the pair to get to the bottom of a gold shipment robbery. Co-written and directed by the great Frank Tashlin (Will Success Spoil Rock Hunter?) and featuring a stellar supporting cast which includes Bill Williams (The Cariboo Trail) and Douglass Dumbrille (Mr. Deeds Goes to Town) with cameos by Bing Crosby (Road to Rio) and legendary director Cecil B. DeMille (Samson and Delilah). "br""br"SPECIAL FEATURES: Audio Commentary by Filmmaker Greg Ford | The Lady Said No - 1946 animated short film by Frank Tashlin

Son of Paleface

CURRENT ISSUE
September, 2021

No. 106 (9)

2020 Impact Factor: 9.941 Submission > Acceptance: 52 days
ARTICLES IN THREE SENTENCES
Article

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma

This open-label, single-arm study investigated the long-term efficacy of tafasitamab plus lenalidomide in 81 patients with relapsed/refractory diffuse large B-cell lymphoma. The response rate was 57.5%, including complete responses in 40.0% of patients, and the median duration of response was 43.9 months. This treatment is a valuable option for patients not eligible for autologous stem-cell transplantation.

Johannes Duell et al.

Case Report

Clinical genomic profiling of novel grey zone lymphoma paired lesions with sequential central nervous system involvement in two adolescent patients

Grey zone lymphoma is a B-cell lymphoma, unclassifiable, with features intermediate between those of large B-cell lymphoma and classic Hodgkin lymphoma. The in-depth study of the two adolescent patients described in this case report expands the clinicopathological and genomic spectrum of this rare pediatric disease. Moreover, it provides information on their response to treatment.

Cagla Y. Benkli et al.

Article

CAMT-MPL: congenital amegakaryocytic thrombocytopenia caused by MPL mutations - heterogeneity of a monogenic disorder - a comprehensive analysis of 56 patients

The clinical picture of 56 patients with congenital amegakaryocytic thrombocytopenia due to MPL mutations was much more varied than previously thought. Twenty-five per cent of them had no signs of thrombocytopenia at birth, and 50% had non-hematologic defects. Pancytopenia developed in (nearly) all patients and hematopoietic stem-cell transplantation was effective in 87% of cases.

Manuela Germeshausen et al.

Article

Oxidative stress activates red cell adhesion to laminin in sickle cell disease

Sickle red blood cells exhibit abnormal adhesion to laminin mediated by Lu/BCAM protein at their surface. This study provides evidence of the involvement of oxidative stress in post-translational modifications of Lu/BCAM which impact the protein’s distribution and cis-interaction with glycophorin C at the cell surface activating its adhesive function in dense sickle red cells. The authors speculate that antioxidant drugs might attenuate this phenomenon.

Maria Alejandra Lizarralde-Iragorri et al.

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